For maximum action, several enzymes need metal ions. A metalloenzyme is one that has a particularly strong metal binding site or needs a metal ion to maintain its stable, natural form. Metal-activated enzymes are those that more sporadically bind metal ions, maybe just during the catalytic cycle. Metals can function as electrophilic catalysts, stabilising the increased electron density or negative charge that might arise during reactions. This is one function for metals in metal-activated enzymes and metalloenzymes. There are several enzymes involved in this. The requirement to reduce operational and capital expenses, catalyst activity, and catalyst stability all have an impact on the choice of the ideal reactor input and output temperatures. Engineering requirements have an impact on the final design inlet temperature selection.