Intracellular Catalysis

The biological environment, which is tightly regulated for the living organism and not always suited for the reaction efficiency of a particular reaction pathway segment, limits intracellular catalysis. A possible method for controlling biological processes is known as "bioorthogonal chemistry," which is any chemical reaction that may take place inside of living systems without interfering with their natural biochemical processes. The toolset of bioorthogonal chemistry for medicinal chemistry and synthetic biology has substantially increased with the introduction of synthetic metal-based catalysts to carry out bioorthogonal processes. Many distinct homogeneous and heterogeneous transition metal catalysts (TMCs) have been identified, mediating various transformations such cycloaddition events as well as bond building and cleaving reactions. However, there are several difficulties with using 'naked' TMCs directly in complex biological environments, including low water solubility, toxicity, and catalyst deactivation. The decorating of the nanocatalysts is employed to give spatiotemporal control of catalysis. TMCs may be incorporated into nanomaterials to form bioorthogonal nanocatalysts, which can solubilize and stabilise catalyst molecules.

Committee Members
Speaker at Catalysis & Reaction Engineering 2026 - Stanislaw Dzwigaj

Stanislaw Dzwigaj

Sorbonne University, France
Speaker at Catalysis & Reaction Engineering 2026 - Dai Yeun Jeong

Dai Yeun Jeong

Asia Climate Change Education Center, Korea, Republic of
Speaker at Catalysis & Reaction Engineering 2026 - Enrico Paris

Enrico Paris

CREA-IT & DIAEE, Italy
Speaker at Catalysis & Reaction Engineering 2026 - Hanna Kierzkowska Pawlak

Hanna Kierzkowska Pawlak

Lodz University of Technology, Poland
CAT 2026 Speakers
Speaker at Catalysis & Reaction Engineering 2026 - Ling Yin

Ling Yin

Cornell University, United States
Speaker at Catalysis & Reaction Engineering 2026 - Tsitsishvili Vladimer

Tsitsishvili Vladimer

Petre Melikishvili Institute of Physical and Organic Chemistry at the Tbilisi State University, Georgia
Speaker at Catalysis & Reaction Engineering 2026 - Rafia Ahmad

Rafia Ahmad

King Abdullah University of Science and Technology, Saudi Arabia
Speaker at Catalysis & Reaction Engineering 2026 - Eun Han Lee

Eun Han Lee

Korea Institute of Energy Research, Korea, Republic of
Speaker at Catalysis & Reaction Engineering 2026 - Neul Ha

Neul Ha

Sungkyunkwan University, Korea, Republic of
Speaker at Catalysis & Reaction Engineering 2026 - Shailza Sharma

Shailza Sharma

RMIT University, Australia
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