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Carboxylation

By treating a substrate with carbon dioxide, a carboxylic acid is created in the process of carboxylation. Decarboxylation is the opposite process. When referring to the reaction of carbanionic reagents with CO2, the terms carbonation and carboxylation can be used interchangeably in chemistry. In a broader sense, carbonation often refers to the creation of carbonates. In organic chemistry, carboxylation is a common conversion. In particular, a traditional method for converting organic halides into carboxylic acids involves carbonation of Grignard reagents and organolithium compounds. Sodium phenolate, the sodium salt of phenol, is treated with carbon dioxide at high pressure (100 atm) and high temperature (390 K) in a process known as the Kolbe-Schmitt reaction to produce sodium salicylate, the precursor of aspirin. the resultant salicylate salt is acidified and gives salicylic acid.

Committee Members
Speaker at Catalysis, Chemical Engineering & Technology 2025 - Stanislaw Dzwigaj

Stanislaw Dzwigaj

Sorbonne University, France
Speaker at Catalysis, Chemical Engineering & Technology 2025 - Thomas J Webster

Thomas J Webster

Interstellar Therapeutics, United States
Speaker at Catalysis, Chemical Engineering & Technology 2025 - Dai Yeun Jeong

Dai Yeun Jeong

Asia Climate Change Education Center, Korea, Republic of
Speaker at Catalysis, Chemical Engineering & Technology 2025 - Vladislav Sadykov

Vladislav Sadykov

Boreskov Institute of Catalysis, Russian Federation
CAT 2025 Speakers
Speaker at Catalysis, Chemical Engineering & Technology 2025 - Beatrice Vincenti

Beatrice Vincenti

Sapienza University of Rome, Italy
Speaker at Catalysis, Chemical Engineering & Technology 2025 - Haibo Ge

Haibo Ge

Texas Tech University, United States
Speaker at Catalysis, Chemical Engineering & Technology 2025 - Pengju Wu

Pengju Wu

School of Energy and Power Engineering Jiangsu University, China
Speaker at Catalysis, Chemical Engineering & Technology 2025 - Yaxin Su

Yaxin Su

Donghua University, China
Speaker at Catalysis, Chemical Engineering & Technology 2025 - Isabel Oller Alberola

Isabel Oller Alberola

Plataforma Solar de Almería, Spain
Speaker at Catalysis, Chemical Engineering & Technology 2025 - Majed Alamoudi

Majed Alamoudi

King Abdulaziz University, Saudi Arabia

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