C-Glycosylations

The glycosidic C—C bond's construction is used by the majority of techniques. These C-glycosylation techniques are grouped here according to the glycosyl donor precursors that are often utilised in the synthesis of O-glycosides and are simple for non-experts to obtain. The glycosyl halides, glycals, sugar acetates, lactones, lactones, lactones, 1,2-anhydro sugars, thioglycosides/sulfoxides/sulfones, selenoglycosides/telluroglycosides, methyl glycosides, and glycosyl imidates/phosphates are some of these substances. Glycosyl electrophilic/cationic species, anionic species, radical species, or transition-metal complexes can all play a role in C-glycosylation processes in terms of their underlying mechanisms, which are covered as subcategories under each kind of sugar precursor. The Claisen, Ramberg-Bäcklund, and 1,2-Wittig rearrangements, which frequently include coordinated pathways, are only a few examples of intramolecular rearrangements. These rearrangements also fall under the category of C-glycosylations. The development of pyranoside/furanoside rings following the creation of the C-glycosylations provides an alternative to the C-glycosylations.