For the production of chemicals and drugs as well as in other fields requiring high selectivity and tolerant reaction conditions, biocatalysis has evolved into a sophisticated technique. As an alternative to chemical catalysis, biocatalysis offers a wide range of uses in several industries. The most notable examples are when enzymes are used in organic synthesis, namely to create chiral chemicals for medicines as well as for the taste and fragrance business. Additionally, the production of speciality and even bulk chemicals uses biocatalysts on a huge scale. Over the past two decades, biocatalysis has grown into a relatively established and often employed technique. Until a few notable exceptions in the early 2000s, biocatalysis remained hidden in specialised applications and concentrated on the synthesis or resolution of optically active intermediates. The quick identification of novel enzyme variations by contemporary bioinformatics and computer-supported enzyme engineering are significant driving forces. Even though the enormous catalytic activity of enzymes is well acknowledged, their stability and expense are sometimes seen as limitations.
Stanislaw Dzwigaj
Sorbonne University, France
Thomas J Webster
Brown University, United States
Dai Yeun Jeong
Asia Climate Change Education Center, Korea, Republic of
Sergey Suchkov
N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Jiri Dedecek
J Heyrovsky Institute of Physical Chemistry , Czech Republic
Vladimir G Chigrinov
Hong Kong University of Science and Technology, Russian Federation
Osman Adiguzel
Firat University, Turkey
Uday Som
Shizuoka University, Japan
Rabeharitsara Andry Tahina
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