In organic chemistry, carbon-carbon bonds are created by the aldol reaction. The reaction, which was independently discovered in 1869 by the Russian scientist Alexander Borodin and in 1872 by the French chemist Charles-Adolphe Wurtz, combines two carbonyl compounds (aldehydes were employed in the initial investigations) to create a new -hydroxy carbonyl compound. These items are referred to as "aldols" since many of the compounds share the structural theme of aldehyde + alcohol. Numerous significant compounds, whether they are created artificially or naturally, include aldol structural units. The aldol reaction, for instance, has been utilised in the mass manufacture of the chemical commodity pentaerythritol and the synthesis of the heart disease medication Lipitor (atorvastatin, calcium salt). The aldol reaction combines two very straightforward compounds into one that is more complicated. Complexity is raised as a result of the production of up to two extra stereogenic centres (on the aldol adduct's carbons, shown by asterisks in the scheme below). In addition to providing high yield aldol reactions, modern approaches may control the relative and absolute configuration of these stereocenters. It is crucial to have the ability to carefully synthesise stereoisomers since they can have distinctive chemical and biological properties.
Stanislaw Dzwigaj
Sorbonne University, France
Thomas J Webster
Interstellar Therapeutics, United States
Dai Yeun Jeong
Asia Climate Change Education Center, Korea, Republic of
Vladislav Sadykov
Boreskov Institute of Catalysis, Russian Federation
Beatrice Vincenti
Sapienza University of Rome, Italy
Haibo Ge
Texas Tech University, United States
Pengju Wu
School of Energy and Power Engineering Jiangsu University, China
Yaxin Su
Donghua University, China
Isabel Oller Alberola
Plataforma Solar de Almería, Spain
Majed Alamoudi
King Abdulaziz University, Saudi ArabiaSubmit your abstract Today
Title : Application of vanadium and tantalum single-site zeolite catalysts in catalysis
Stanislaw Dzwigaj, Sorbonne University, France
Title : 30,000 nano implants in humans with no infections, no loosening, and no failures
Thomas J Webster, Interstellar Therapeutics, United States
Title : Solar heterogeneous photocatalysis and photochemistry for urban wastewater regeneration and reuse
Isabel Oller Alberola, Plataforma Solar de Almería, Spain
Title : Personalized and Precision Medicine (PPM) as a unique healthcare model through biodesign-inspired & biotech-driven translational applications and upgraded business marketing to secure the human healthcare and biosafety
Sergey Suchkov, R&D Director of the National Center for Human Photosynthesis, Mexico
Title : Human impact on natural environment and its implications
Dai Yeun Jeong, Asia Climate Change Education Center, Korea, Republic of
Title : Effect of bed material on syngas quality: Comparison of biomass gasification with different bed materials
Enrico Paris, CREA-IT & DIAEE, Italy
Title : Valorizing lignocellulose to ethylene glycol: Catalysis, catalyst deactivation and conceptual process design
Jean Paul Lange, University of Twente, Netherlands
Title : Design of nanocomposite materials for active components of structured catalysts for biofuels transformation into syngas, catalytic layers of membrane reactors with oxygen/hydrogen separation and anodes of solid oxide fuels cells operating in the internal reforming mode
Vladislav Sadykov, Boreskov Institute of Catalysis, Russian Federation
Title : Cleaner syngas from biomass gasification: Is K-Feldspar the key?
Beatrice Vincenti, Sapienza University of Rome, Italy
Title : Scalable synthesis of the PEM electrolysis anode material
Inayat Ali Khan, University of Southern Denmark, Denmark