Jian He graduated from Jilin University in China. She is in expert in pharmacology and drug discovery.
A new cobalt-based heterogeneous catalyst was prepared by adsorbing in situ produced nitrogen-ligated cobalt (II) acetate complexes on commercially available SiO2 and subsequent pyrolysis at 800 °C for 2 h under N2 atmosphere. By applying this catalyst under the O2 balloon, the aerobic oxidation of phenolic imines proceeded smoothly and gave various 2-arylbenzoxazoles in good yields. Meanwhile, on the basis of the experimental results, a plausible reaction pathway was described to elucidate the reaction mechanism.
Audience Take away:
• We have designed a CoOx-NGr/SiO2 nanocomposite catalyst for the aerobic oxidation of phenolic imines to give various benzoxazoles in good to excellent yields.
• We believe that this strategy is attractive for the design of other heterogeneous metal catalysts. Further extension application of this catalytic system for the preparation of some other kind of useful heterocyclic compounds is underway in our laboratory.