Title : Chemoselective Transfer Hydrogenation of Multifunctional Nitro Compouds Catalyzed by Silver Nanoparticles: A Facile Synthetic Methodology towards Dihydroquinoxalin 2 ones
Abstract:
The catalytic hydrogenation of nitro compounds is one of the most important chemical reactions as the product amines are forceful intermediates for the synthesis of various natural and industrial products like agrochemicals, pharmaceuticals, dyes, and polymers.1 Through the Multi-Component Reactions (MCRs), which are an important method since carbon-carbon, carbon-nitrogen and carbon-oxygen bonds are created in a single stage,2 the facile mesoporous silica-supported silver and gold nanoparticles catalyzed chemoselective reduction of multifunctional nitro-compounds into the corresponding amines in high isolated yields, employing NaBH4 or Et3SiH as reducing agents,3 is reported. The present catalytic system represents an rattling approach towards the production of the heterocyclic bioactive compounds of dihydroquinoxalin-2-ones with high yields, via a catalytic two-step one-pot ring closing pathway based on the reported chemoselective reduction.
