HYBRID EVENT: You can participate in person at Valencia, Spain or Virtually from your home or work.
Moaz M Abdou, Speaker at Chemical Engineering Conferences
Egyptian Petroleum Research Institute, Egypt
Title : Catalytic esterification for the efficient synthesis of phosphinic dipeptides and their acetylated glucose derivatives

Abstract:

The successful synthesis of novel phosphinic dipeptides and their acetylated glucose derivatives via an efficient esterification process is reported. Reaction of phosphinic dipeptides with 1,2,3,4-tetra-O-acetyl-β-D-glucopyranose (TGA) afforded carbohydrate-based phosphinic esters in high yield. This streamlined methodology simplifies the production process while providing a versatile platform for further structural modifications. The smooth synthesis of both the dipeptide and TGA-derived ester frameworks lays the foundation for the development of well-known phosphinic protease inhibitors and their corresponding sugar conjugates. The presentation details the synthetic strategies employed, the optimized reaction conditions, and the potential impact of these compounds in drug design.

Biography:

Moaz M. Abdou is an Assistant Professor of Applied Organic Chemistry at the Egyptian Petroleum Research Institute in Cairo. He earned his Ph.D. from the University of Liverpool and completed postdoctoral research at the Chinese Academy of Sciences. With extensive experience in Japan and the UK, his work focuses on the synthesis of innovative organic compounds for applications in energy, environment, and medicine. Recognized among the top 2% of scientists worldwide, he has published over 50 research papers and actively contributes as a peer reviewer and editor in leading scientific journals.

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