Title : Bimetallic catalysts for the hydrogenation of amides: From experimental to data-driven insights
Abstract:
This work evaluates the impact of various parameters on bimetallic catalysts in the hydrogenation of amides to amines, using systematic experimental and data-driven methods. Bimetallic catalysts were synthesized via a sequential wet impregnation approach and tested on the hydrogenation of N,N-dimethyldodecanamide to N,N- dimethyldodecanamine. The choice of metal precursors, supports, and the oxophilic metal significantly influenced the catalytic performance. Data-driven analysis indicated that oxophilic metals with large electronegativity and weak O adsorption displayed higher conversion, whereas those with large enthalpy of fusion, higher amine selectivity.
