Nanomaterials have been widely tested in vitro and in small order animal studies for decades. Results have shown greater tissue growth, decreased bacteria growth, and inhibited inflammation. However, few, if any, studies exist examining human tissue response to nanomaterials. This study represents a cohort study of nano implants inserted into the spine of over 14,000 patients over the past 5 years. Results demonstrated no cases of infections or other implant failures which is significantly better than statistics on conventional spinal implants which have up to 20% failure rates. This study will further explain that nano implants mimic the natural nano texture of bone itself and possess surface energy that can competitively increase the adsorption of proteins known to promote osteoblast (bone forming cells) functions, decrease bacteria functions, and limit inflammatory cell functions. As such, this study represents one of the few human clinical studies on nano implants.
Audience Take Away:
- Human clinical data for nano implants
- How nano implants can increase tissue growth
- How nano implants can decrease infection without antibiotics
- How nano implants can reduce inflammation