HYBRID EVENT: You can participate in person at Valencia, Spain or Virtually from your home or work.
Tahany Mahmoud Mohamed Ahmed, Speaker at Catalysis Conferences
Minia University, Egypt
Title : Visible Light in Heterocyclic Chemistry: An efficient and Environmentally Friendly Protocol for the Synthesis Polyfunctionalized Substituted Cinnolines


Visible light has evolved into a widely used for many types of transformations in organic synthesis. Cinnolines are interesting classes of heterocycles owing to their strong pharmaceutical and medicinal activities. In the current study, we developed a simple and efficient synthesis of polyfunctionalized substituted cinnoline derivatives (3) that relied on reaction of ethyl 5-cyano-4-methyl-1-aryl-6-oxo-1,6-dihydropyridazine-3-carboxylates with nitrostyrene in visible light (White LED, 30 W) and catalysed by piperidine with ethanol as a solvent. This method seems to be green, simple and with high atom economy.

Audience take-away:

  • This work provides a facile method for the synthesis of bioactive cinnolines.
  • It will encourage synthetic chemists to use visible light as an alternative approach.
  • It will contribute to the idea of making chemistry greener.


Mrs. Tahany Mahmoud Mohamed studied Chemistry at Sohag University, Egypt and graduated with BSC in 2000. She works as a senior chemist at Sohag Cancer institute. She joined the research group of Prof. Kamal Usef Sadek at Faculty of Science, Minia University and graduated as MS in 2012. With Prof. Sadek group, she is going to finish PhD degree by the end of this year.