Naturally fallen red cotton flowers are available in plenty in North-East of India, especially in Assam. It is known that these flowers are traditionally being used to prepare cleansing agents in some parts of the state. Our investigation focused on converting these flowers into a catalyst for industrial applications. The catalyst prepared in our laboratory has been successfully tested and used in transesterification reactions, and it is found that the catalyst is quite efficient in the process of biodiesel preparation from vegetable oils. The presentation will describe the methodology for the preparation of the catalyst, studies done on its efficiency in transesterication reations including biodiesel preparation and the reusability of the catalyst.